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Theses 2021

At this place we provide an overview of the various PhD Theses that were produced within SILS. A link to the full text of the thesis is provided. SILS Theses before 2014 are available via dare.uva.nl.

Developing and analysing novel tools to study endogenous WNT signalling in mice

Anoeska van de Moosdijk

16 November 2021

Supervisors: T.W.J. Gadella, R. van Amerongen

Research Group: Developmental, Stem Cell and Cancer Biology

Uva DARE: This thesis online

Metabolic programming by early-life stress exposure

Focus on sex differences

Silvie Ruigrok

4 November 2021

Supervisors: A. Korosi, P.J. Lucassen

Research Group: Structural and Functional Plasticity of the Nervous System

Uva DARE: This thesis online

Identification and characterization of Tomato spotted wilt orthotospovirus pro-viral factors as a source for durable resistance

Tieme Helderman

19 October 2021

Supervisors: M.W. Prins, H.A. van den Burg

Research Group: Molecular Plant Pathology

Uva DARE: This thesis online

Composition, evolution and transfer of resistance plasmids in Escherichia coli

Tania Darphorn

13 October 2021

Supervisors: B.H. ter Kuile, S. Brul

Research Group: Molecular Biology and Microbial Food Safety

Uva DARE: This thesis online

Exploring the Wnt enhancer landscape in the mammary gland

Nika Heijmans

7 July 2021

Supervisors: T.W.J. Gadella, R. van Amerongen

Research Group: Molecular Cytology

Uva DARE: This thesis online

Heterogeneity of the immunopathology in advanced multiple sclerosis

An autopsy cohort analysis

Nina Fransen (Doctorate awarded Cum Laude)

2 July 2021

Supervisors: I. Huitinga, J. Smolders

Research Group: NIN

Uva DARE: This thesis online

Photoautotrophic overproduction of mannitol in Synechocystis sp. PCC6803 using osmotic pressure as a driving force

Wenyang Wu

30 June 2021

Supervisors: F. Branco dos Santos, L.W. Hamoen

Research Group: Bacterial Cell Biology and Physiology 

Uva DARE: This thesis online

Metabolomic and genomic investigation into the actinomycete genus Planomonospora

Mitja Zdouc

28 June 2021

Supervisors: T. den Blaauwen, M. Sosio, L.W. Hamoen

Research Group: Bacterial Cell Biology

Uva DARE: This thesis online

Dynamics of TNF during TNF inhibitor treatment

Lea Berkhout

23 June 2021

Supervisors: S.M. van Ham, M.T. Nurmohamed, T. Rispens, G.J. Wolbink

Research Group: Sanquin

Uva DARE: This thesis online

Defining meiotic recombination landscape in tomato

Jihed Chouaref

3 June 2021

Supervisors: R.E. Koes, P.F. Fransz

Research Group: Plant Development & (Epi)genetics 

Uva DARE: This thesis online

Proteome dynamics during sporulation and heat resistance in Bacillus subtilis spores

Zhiwei Tu

27 May 2021

Supervisors: S. Brul, G. Kramer

Research Group: Molecular Biology and Microbial Food Safety & Mass Spectrometry of Biomolecules

Uva DARE: This thesis online

Tuning the show

Genetic engineering to unravel antigen presentation by the human leukocyte antigen class I

Twan de Waard

19 May 2021

Supervisors: S.M. van Ham, R.M. Spaapen

Host institution: Sanquin

Uva DARE: This thesis online

Improving the synthetic biology toolbox of Synechocystis sp. PCC 6803

Patricia Caicedo Burbano

7 April 2021

Supervisors: L.W. Hamoen, F. Branco dos Santos

Research Group: Bacterial Cell Biology and Physiology

Uva DARE: This thesis online

Mcl1 in control of life and death of dopamine neurons

Eddy Robinson

2 March 2021

Supervisors: M.P. Smidt, L.P. van der Heide

Research Group: Molecular Neuroscience

Uva DARE: This thesis online

Gene-regulation & epigenetics in dopaminergic neurons

New roles for Dot1l and Af9 in balanced synaptic versus mitochondrial neuronal gene regulation

Erik van Heesbeen

3 February 2021

Supervisors: M.P. Smidt

Research Group: Molecular Neuroscience

Uva DARE: This thesis online

Segmental duplications as a source of innovation in brain development

Gerrald Lodewijk (Doctorate awarded Cum Laude)

13 January 2021

Supervisors: M.P. Smidt, F.M.J. Jacobs

Research Group: Molecular Neuroscience

Uva DARE: This thesis online