2O21

A vascular odyssey

Sofia Morsing

3 December 2021

Supervisors: J.D. van Buul, A.P.J. Vlaar, R. Kapur

Research Group: Molecular Cell biology (Sanquin)

Uva DARE: This thesis online

The role of epigenetics in transcriptional stochasticity and the implications for breast cancer drug resistance

Will Beckman

1 December 2021

Supervisors: P.J. Verschure, A.H.C. van Kampen

Research Group: Synthetic Systems Biology and Nuclear Organisation

Uva DARE: This thesis online

Developing and analysing novel tools to study endogenous WNT signalling in mice

Anoeska van de Moosdijk

16 November 2021

Supervisors: T.W.J. Gadella, R. van Amerongen

Research Group: Developmental, Stem Cell and Cancer Biology

Uva DARE: This thesis online

Metabolic programming by early-life stress exposure

Focus on sex differences

Silvie Ruigrok

4 November 2021

Supervisors: A. Korosi, P.J. Lucassen

Research Group: Structural and Functional Plasticity of the Nervous System

Uva DARE: This thesis online

Identification and characterization of Tomato spotted wilt orthotospovirus pro-viral factors as a source for durable resistance

Tieme Helderman

19 October 2021

Supervisors: M.W. Prins, H.A. van den Burg

Research Group: Molecular Plant Pathology

Uva DARE: This thesis online

Composition, evolution and transfer of resistance plasmids in Escherichia coli

Tania Darphorn

13 October 2021

Supervisors: B.H. ter Kuile, S. Brul

Research Group: Molecular Biology and Microbial Food Safety

Uva DARE: This thesis online

Exploring the Wnt enhancer landscape in the mammary gland

Nika Heijmans

7 July 2021

Supervisors: T.W.J. Gadella, R. van Amerongen

Research Group: Molecular Cytology

Uva DARE: This thesis online

Heterogeneity of the immunopathology in advanced multiple sclerosis

An autopsy cohort analysis

Nina Fransen (Doctorate awarded Cum Laude)

2 July 2021

Supervisors: I. Huitinga, J. Smolders

Research Group: NIN

Uva DARE: This thesis online

Photoautotrophic overproduction of mannitol in Synechocystis sp. PCC6803 using osmotic pressure as a driving force

Wenyang Wu

30 June 2021

Supervisors: F. Branco dos Santos, L.W. Hamoen

Research Group: Bacterial Cell Biology and Physiology 

Uva DARE: This thesis online

Metabolomic and genomic investigation into the actinomycete genus Planomonospora

Mitja Zdouc

28 June 2021

Supervisors: T. den Blaauwen, M. Sosio, L.W. Hamoen

Research Group: Bacterial Cell Biology

Uva DARE: This thesis online

Dynamics of TNF during TNF inhibitor treatment

Lea Berkhout

23 June 2021

Supervisors: S.M. van Ham, M.T. Nurmohamed, T. Rispens, G.J. Wolbink

Research Group: Sanquin

Uva DARE: This thesis online

Defining meiotic recombination landscape in tomato

Jihed Chouaref

3 June 2021

Supervisors: R.E. Koes, P.F. Fransz

Research Group: Plant Development & (Epi)genetics 

Uva DARE: This thesis online

Proteome dynamics during sporulation and heat resistance in Bacillus subtilis spores

Zhiwei Tu

27 May 2021

Supervisors: S. Brul, G. Kramer

Research Group: Molecular Biology and Microbial Food Safety & Mass Spectrometry of Biomolecules

Uva DARE: This thesis online

Tuning the show

Genetic engineering to unravel antigen presentation by the human leukocyte antigen class I

Twan de Waard

19 May 2021

Supervisors: S.M. van Ham, R.M. Spaapen

Host institution: Sanquin

Uva DARE: This thesis online

Improving the synthetic biology toolbox of Synechocystis sp. PCC 6803

Patricia Caicedo Burbano

7 April 2021

Supervisors: L.W. Hamoen, F. Branco dos Santos

Research Group: Bacterial Cell Biology and Physiology

Uva DARE: This thesis online

Mcl1 in control of life and death of dopamine neurons

Eddy Robinson

2 March 2021

Supervisors: M.P. Smidt, L.P. van der Heide

Research Group: Molecular Neuroscience

Uva DARE: This thesis online

Gene-regulation & epigenetics in dopaminergic neurons

New roles for Dot1l and Af9 in balanced synaptic versus mitochondrial neuronal gene regulation

Erik van Heesbeen

3 February 2021

Supervisors: M.P. Smidt

Research Group: Molecular Neuroscience

Uva DARE: This thesis online

Segmental duplications as a source of innovation in brain development

Gerrald Lodewijk (Doctorate awarded Cum Laude)

13 January 2021

Supervisors: M.P. Smidt, F.M.J. Jacobs

Research Group: Molecular Neuroscience

Uva DARE: This thesis online