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Microorganisms play a central role in our existence. They help to digest our food, and they are used to preserve food. Yet, they can spoil food and can poison us. They cause life-threatening infections but also produce the antibiotics that save us. They play key roles in nature as they help the global recycling of nutrients and energy. Considering their importance, it is surprising how little we know about their workings.

SILS Microbiology Theme

We study the intricate dynamics of microorganisms and their interactions with hosts, in particularly the human microbiome. Our ultimate goal is to translate the obtained knowledge into innovative applications that benefit health, industry, and the environment.

On the Side of the Microorganism

We study fundamental aspects of bacterial growth, how they communicate through RNA-based and other means, how they adapt and differentiate, and how they evolve antibiotic resistance. In addition, we examine how we can develop novel antibiotics, control food spoilage causing bacteria, optimize microbial metabolic processes to improve chemical and enzyme production, and convert CO2 into useful products using photosynthetic cell factories.

On the Side of the Host

We study how the intestinal microbiome and host interact, and what impact this has on health at different stages of life, how can we engineer microbial consortia to benefit the host, and what insights can be gained from gut-microbiome-on-a-chip technology, how do host-microbe interactions influence overall health.

Research groups of the Microbiology Theme:

Principal Investigators (PI's):

Prof. dr. S. (Stanley) Brul

Faculty of Science

Swammerdam Institute for Life Sciences

Dr. M.T. (Meike) Wortel

Faculty of Science

Swammerdam Institute for Life Sciences

Dr J. (Jianbo) Zhang

Faculty of Science

Swammerdam Institute for Life Sciences

Prof. dr. ir. L.P.B. (Linda) Verhoef

Faculty of Science

Swammerdam Institute for Life Sciences

Prof. dr. S. (Sahar) El Aidy PhD

Faculty of Science

Swammerdam Institute for Life Sciences

Prof. dr. L.W. (Leendert) Hamoen

Faculty of Science

Swammerdam Institute for Life Sciences

Dr. G. (Gaurav) Dugar

Faculty of Science

Swammerdam Institute for Life Sciences

Dr. F. (Filipe) Branco dos Santos

Faculty of Science

Swammerdam Institute for Life Sciences

Dr. G. (Gertjan) Kramer

Faculty of Science

Swammerdam Institute for Life Sciences

Collaborations

The Microbiology theme is part of the UvA Research Priority Area Personal Microbiome Health and the Faculty Research Priority Area Systems Biology (Host-Microbiome Interactions). The Microbiology community in Amsterdam is further organized in the Amsterdam Microbiome Expertise Center. 

Amsterdam Microbiome Expertise Center

The Amsterdam Microbiome Expertise Center (AMEC) is an Amsterdam wide initiative to bundle the expertise available in our area at the UvA, VU, Amsterdam UMC and ACTA. Its members meet at the Amsterdam Microbiology SeminArs (AMSA) and aim to study microbial consortia in biotechnological, biomedical and environmental settings using multidisciplinary approaches.