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Mekkes, N. J., Groot, M., Hoekstra, E., de Boer, A., Dagkesamanskaia, E., Bouwman, S., Wehrens, S. M. T., Herbert, M. K., Wever, D. D., Rozemuller, A., Eggen, B. J. L., Huitinga, I., & Holtman, I. R. (2024). Identification of clinical disease trajectories in neurodegenerative disorders with natural language processing. Nature medicine, 30(4), 1143-1153. https://doi.org/10.1038/s41591-024-02843-9[details]
Hsiao, C. C., Engelenburg, H. J., Jongejan, A., Zhu, J., Zhang, B., Mingueneau, M., Moerland, P. D., Huitinga, I., Smolders, J., & Hamann, J. (2023). Osteopontin associates with brain TRM-cell transcriptome and compartmentalization in donors with and without multiple sclerosis. iScience, 26(1), Article 105785. https://doi.org/10.1016/j.isci.2022.105785
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Scheepstra, K. W. F., Mizee, M. R., van Scheppingen, J., Adelia, A., Wever, D. D., Mason, M. R. J., Dubbelaar, M. L., Hsiao, C. C., Eggen, B. J. L., Hamann, J., & Huitinga, I. (2023). Microglia Transcriptional Profiling in Major Depressive Disorder Shows Inhibition of Cortical Gray Matter Microglia. Biological Psychiatry, 94(8), 619-629. https://doi.org/10.1016/j.biopsych.2023.04.020[details]
van den Bosch, A. M. R., Hümmert, S., Steyer, A., Ruhwedel, T., Hamann, J., Smolders, J., Nave, K. A., Stadelmann, C., Kole, M. H. P., Möbius, W., & Huitinga, I. (2023). Ultrastructural Axon–Myelin Unit Alterations in Multiple Sclerosis Correlate with Inflammation. Annals of Neurology, 93(4), 856-870. https://doi.org/10.1002/ana.26585
2021
Zhang, L., Verwer, R. W. H., Zhao, J., Huitinga, I., Lucassen, P. J., & Swaab, D. F. (2021). Changes in glial gene expression in the prefrontal cortex in relation to major depressive disorder, suicide and psychotic features. Journal of Affective Disorders, 295, 893-903. https://doi.org/10.1016/j.jad.2021.08.098[details]
Böttcher, C., van der Poel, M., Fernández-Zapata, C., Schlickeiser, S., Leman, J. K. H., Hsiao, C-C., Mizee, M. R., Adelia, Vincenten, M. C. J., Kunkel, D., Huitinga, I., Hamann, J., & Priller, J. (2020). Single-cell mass cytometry reveals complex myeloid cell composition in active lesions of progressive multiple sclerosis. Acta Neuropathologica Communications, 8, Article 136. https://doi.org/10.1186/s40478-020-01010-8[details]
Fransen, N. L., Hsiao, C-C., van der Poel, M., Engelenburg, H. J., Verdaasdonk, K., Vincenten, M. C. J., Remmerswaal, E. B. M., Kuhlmann, T., Mason, M. R. J., Hamann, J., Smolders, J., & Huitinga, I. (2020). Tissue-resident memory T cells invade the brain parenchyma in multiple sclerosis white matter lesions. Brain, 143(6), 1714-1730. https://doi.org/10.1093/brain/awaa117[details]
Korotkov, A., Puhakka, N., Das Gupta, S., Vuokila, N., Broekaart, D. W. M., Anink, J. J., Heiskanen, M., Karttunen, J., van Scheppingen, J., Huitinga, I., Mills, J. D., van Vliet, E. A., Pitkänen, A., & Aronica, E. (2020). Increased expression of miR142 and miR155 in glial and immune cells after traumatic brain injury may contribute to neuroinflammation via astrocyte activation. Brain Pathology, 30(5), 897-912. Advance online publication. https://doi.org/10.1111/bpa.12865[details]
Zhang, L., Verwer, R. W. H., Lucassen, P. J., Huitinga, I., & Swaab, D. F. (2020). Prefrontal cortex alterations in glia gene expression in schizophrenia with and without suicide. Journal of Psychiatric Research, 121, 31-38. Advance online publication. https://doi.org/10.1016/j.jpsychires.2019.11.002[details]
Zhang, L., Verwer, R. W. H., Lucassen, P. J., Huitinga, I., & Swaab, D. F. (2020). Sex difference in glia gene expression in the dorsolateral prefrontal cortex in bipolar disorder: Relation to psychotic features. Journal of Psychiatric Research, 125, 66-74. Advance online publication. https://doi.org/10.1016/j.jpsychires.2020.03.003[details]
van der Poel, M., Hoepel, W., Hamann, J., Huitinga, I., & den Dunnen, J. (2020). IgG Immune Complexes Break Immune Tolerance of Human Microglia. The journal of immunology, 205(9), 2511-2518. https://doi.org/10.4049/jimmunol.2000130[details]
2021
Hsiao, C-C., Fransen, N. L., van den Bosch, A. M. R., Brandwijk, K. I. M., Huitinga, I., Hamann, J., & Smolders, J. (2021). White matter lesions in multiple sclerosis are enriched for CD20dim CD8+ tissue-resident memory T cells. European journal of immunology, 51(2), 483-486. Advance online publication. https://doi.org/10.1002/eji.202048665[details]
2021
Fransen, N. L. (2021). Heterogeneity of the immunopathology in advanced multiple sclerosis: An autopsy cohort analysis. [Thesis, externally prepared, Universiteit van Amsterdam]. [details]
Kalsbeek, M. J. T. (2020). Neuron-glia interactions in patients with type 2 diabetes. [Thesis, externally prepared, Universiteit van Amsterdam]. [details]
van der Poel, M. (2020). Diversity of microglia: Their contribution to multiple sclerosis lesion formation. [Thesis, externally prepared, Universiteit van Amsterdam]. [details]
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