Prof. dr. H.W.H.G. (Helmut) Kessels
Faculty of Science
Swammerdam Institute for Life Sciences
Visiting address
- Science Park 904
Postal address
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Postbus 94246
1090 GE Amsterdam
Contact details
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Publications
2025
Lucassen, P. J., Korosi, A., de Rooij, S. R., Smit, A. B., Van Dam, A.-M., Daskalakis, N. P., Van Kesteren, R. E., Verheijen, M. H. G., Lesuis, S. L., Kessels, H. W., & Krugers, H. J. (2025). How Can Early Stress Influence Later Alzheimer's Disease Risk? Possible Mediators and Underlying Mechanisms. Biological Psychiatry, 97(4), 372-381. https://doi.org/10.1016/j.biopsych.2024.11.007 [details]- Willems, T. S., Xiong, H., Kessels, H. W., & Lesuis, S. L. (2025). GluA1-containing AMPA receptors are necessary for sparse memory engram formation. Neurobiology of Learning and Memory, 218, 108031. Advance online publication. https://doi.org/10.1016/j.nlm.2025.108031
2024
- Cabrera, Y., Koymans, K. J., Poe, G. R., Kessels, H. W., Van Someren, E. J. W., & Wassing, R. (2024). Overnight neuronal plasticity and adaptation to emotional distress. Nature Reviews Neuroscience, 25(4), 253-271. https://doi.org/10.1038/s41583-024-00799-w [details]
- Martins, I. M., Lima, A., de Graaff, W., Cristóvão, J. S., Brosens, N., Aronica, E., Kluskens, L. D., Gomes, C. M., Azeredo, J., & Kessels, H. W. (2024). M13 phage grafted with peptide motifs as a tool to detect amyloid-β oligomers in brain tissue. Communications biology, 7, Article 134. https://doi.org/10.1038/s42003-024-05806-5 [details]
- de Vries, L. E., Huitinga, I., Kessels, H. W., Swaab, D. F., & Verhaagen, J. (2024). The concept of resilience to Alzheimer's Disease: current definitions and cellular and molecular mechanisms. Molecular Neurodegeneration, 19, Article 33. https://doi.org/10.1186/s13024-024-00719-7 [details]
2023
- Brosens, N., Simon, C., Kessels, H. W., Lucassen, P. J., & Krugers, H. J. (2023). Early life stress lastingly alters the function and AMPA-receptor composition of glutamatergic synapses in the hippocampus of male mice. Journal of Neuroendocrinology, 35(12), Article e13346. https://doi.org/10.1111/jne.13346 [details]
- Lumeij, L. B., van Huijstee, A. N., Cappaert, N. L. M., & Kessels, H. W. (2023). Variance analysis as a method to predict the locus of plasticity at populations of non-uniform synapses. Frontiers in Cellular Neuroscience, 17, Article 1232541. https://doi.org/10.3389/fncel.2023.1232541 [details]
- Zhang, T., Musheshe, N., van der Veen, C. H. J. T. M., Kessels, H. W., Dolga, A., De Deyn, P., Eisel, U., & Schmidt, M. (2023). The Expression of Epac2 and GluA3 in an Alzheimer's Disease Experimental Model and Postmortem Patient Samples. Biomedicines, 11(8), Article 2096. https://doi.org/10.3390/biomedicines11082096 [details]
2021
- Dore, K., Carrico, Z., Alfonso, S., Marino, M., Koymans, K., Kessels, H. W., & Malinow, R. (2021). PSD-95 protects synapses from β-amyloid. Cell Reports, 35(9), Article 109194. https://doi.org/10.1016/j.celrep.2021.109194 [details]
- Grieco, F., Bernstein, B. J., Biemans, B., Bikovski, L., Burnett, C. J., Cushman, J. D., van Dam, E. A., Fry, S. A., Richmond-Hacham, B., Homberg, J. R., Kas, M. J. H., Kessels, H. W., Koopmans, B., Krashes, M. J., Krishnan, V., Logan, S., Loos, M., McCann, K. E., Parduzi, Q., ... Noldus, L. P. J. J. (2021). Measuring Behavior in the Home Cage: Study Design, Applications, Challenges, and Perspectives. Frontiers in Behavioral Neuroscience, 15, Article 735387. https://doi.org/10.3389/fnbeh.2021.735387 [details]
- Zimmer, T. S., David, B., Broekaart, D. W. M., Schidlowski, M., Ruffolo, G., Korotkov, A., van der Wel, N. N., van Rijen, P. C., Mühlebner, A., van Hecke, W., Baayen, J. C., Idema, S., François, L., van Eyll, J., Dedeurwaerdere, S., Kessels, H. W., Surges, R., Rüber, T., Gorter, J. A., ... Aronica, E. (2021). Seizure-mediated iron accumulation and dysregulated iron metabolism after status epilepticus and in temporal lobe epilepsy. Acta Neuropathologica, 142(4), 729-759. https://doi.org/10.1007/s00401-021-02348-6 [details]
2020
- Krugers, H., Kessels, H., & Lucassen, P. (2020). Plasticiteit in de hersenen; synaptische plasticiteit en adulte neurogenese. In O. van den Heuvel, Y. van den Werf, B. Schmand, & B. Sabbe (Eds.), Leerboek neurowetenschappen voor de klinische psychiatrie (pp. 52-58). Boom. [details]
- van Huijstee, A. N., & Kessels, H. W. (2020). Variance analysis as a tool to predict the mechanism underlying synaptic plasticity. Journal of Neuroscience Methods, 331, Article 108526. https://doi.org/10.1016/j.jneumeth.2019.108526 [details]
2019
- Uyaniker, S., van der Spek, S. J. F., Reinders, N. R., Xiong, H., Li, K. W., Bossers, K., Smit, A. B., Verhaagen, J., & Kessels, H. W. (2019). The Effects of Sindbis Viral Vectors on Neuronal Function. Frontiers in Cellular Neuroscience, 13, Article 362. https://doi.org/10.3389/fncel.2019.00362 [details]
2018
- Lesuis, S. L., Hoeijmakers, L., Korosi, A., de Rooij, S. R., Swaab, D. F., Kessels, H. W., Lucassen, P. J., & Krugers, H. J. (2018). Vulnerability and resilience to Alzheimer's disease: early life conditions modulate neuropathology and determine cognitive reserve. Alzheimer's Research & Therapy, 10, Article 95. https://doi.org/10.1186/s13195-018-0422-7 [details]
- Zhao, J., Verwer, R. W. H., Gao, S-F., Qi, X-R., Lucassen, P. J., Kessels, H. W., & Swaab, D. F. (2018). Prefrontal alterations in GABAergic and glutamatergic gene expression in relation to depression and suicide. Journal of Psychiatric Research, 102, 261-274. Advance online publication. https://doi.org/10.1016/j.jpsychires.2018.04.020 [details]
2017
- Gutierrez-Castellanos, N., Da Silva-Matos, C. M., Zhou, K., Canto, C. B., Renner, M. C., Koene, L. M. C., Ozyildirim, O., Sprengel, R., Kessels, H. W., & de Zeeuw, C. I. (2017). Motor Learning Requires Purkinje Cell Synaptic Potentiation through Activation of AMPA-Receptor Subunit GluA3. Neuron, 93(2), 409-424. Advance online publication. https://doi.org/10.1016/j.neuron.2016.11.046
- Renner, M. C., Albers, E. H. H., Gutierrez-Castellanos, N., Reinders, N. R., van Huijstee, A. N., Xiong, H., Lodder, T. R., & Kessels, H. W. (2017). Synaptic Plasticity through Activation of GluA3-containing AMPA-receptors. eLife, 6, Article e25462. https://doi.org/10.7554/eLife.25462
2016
- Reinders, N. R., Pao, Y., Renner, M. C., da Silva-Matos, C. M., Lodder, T. R., Malinow, R., & Kessels, H. W. (2016). Amyloid-β effects on synapses and memory require AMPA-receptor subunit GluA3. Proceedings of the National Academy of Sciences of the United States of America.
2014
- Lohmann, C., & Kessels, H. W. (2014). The developmental stages of synaptic plasticity. Journal of Physiology. https://doi.org/10.1113/jphysiol.2012.235119
- Wang, F., Kessels, H. W., & Hu, H. (2014). The mouse that roared: neural mechanisms of social hierarchy. Trends in Neurosciences.
2013
- Kessels, H. W., Nabavi, S., & Malinow, R. (2013). Metabotropic NMDA receptor function is required for beta-amyloid-induced synaptic depression. Proceedings of the National Academy of Sciences of the United States of America.
- Nabavi, S., Kessels, H. W., Alphonso, S., Aow, J., Fox, R., & Malinow, R. (2013). Metabotropic NMDA receptor function is required for NMDA receptor-dependent long-term depression. Proceedings of the National Academy of Sciences of the United States of America.
2010
- Kessels, H. W., Nguyen, L. N., Nabavi, S., & Malinow, R. (2010). The prion protein as a receptor for amyloid-beta. Nature.
Prize / grant
- Kessels, H. (2014). The Alzheimer Prize.
2025
2024
2022
2020
2019
2018
This list of publications is extracted from the UvA-Current Research Information System. Questions? Ask the library or the Pure staff of your faculty / institute. Log in to Pure to edit your publications. Log in to Personal Page Publication Selection tool to manage the visibility of your publications on this list. -
Ancillary activities
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Alzheimer Nederland
Lid Wetenschappelijke Advies Raad
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Alzheimer Nederland
Lucassen, P. J., Korosi, A., de Rooij, S. R., Smit, A. B., Van Dam, A.-M., Daskalakis, N. P., Van Kesteren, R. E., Verheijen, M. H. G., Lesuis, S. L., Kessels, H. W., & Krugers, H. J. (2025). How Can Early Stress Influence Later Alzheimer's Disease Risk? Possible Mediators and Underlying Mechanisms. Biological Psychiatry, 97(4), 372-381.