Dr. J.A. (Jan) Gorter
Faculty of Science
Swammerdam Institute for Life Sciences
Visiting address
- Science Park 904
- Room number: C3.266
Postal address
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Postbus 94246
1090 GE Amsterdam
Contact details
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Publications
2025
Rozeboom, A., Broekaart, D. W. M., Anink, J. J., Boonkamp, L., Idema, S., Teunissen, C. E., Aronica, E., Gorter, J. A., & van Vliet, E. A. (2025). Cellular expression of low-density lipoprotein receptor-related protein 1 and amyloid beta deposition in human and rat epileptogenic brain. Experimental Neurology, 386, Article 115149. https://doi.org/10.1016/j.expneurol.2025.115149 [details]
2024
- Meeusen, H., Kalf, R. S., Broekaart, D. W. M., Silva, J. P., Verkuyl, J. M., van Helvoort, A., Gorter, J. A., van Vliet, E. A., & Aronica, E. (2024). Effective reduction in seizure severity and prevention of a fatty liver by a novel low ratio ketogenic diet composition in the rapid kindling rat model of epileptogenesis. Experimental Neurology, 379, Article 114861. https://doi.org/10.1016/j.expneurol.2024.114861 [details]
- Meeusen, H., Romagnolo, A., Holsink, S. A. C., van den Broek, T. J. M., van Helvoort, A., Gorter, J. A., van Vliet, E. A., Verkuyl, J. M., Silva, J. P., & Aronica, E. (2024). A novel hepatocyte ketone production assay to help the selection of nutrients for the ketogenic diet treatment of epilepsy. Scientific Reports, 14(1), Article 11940. https://doi.org/10.1038/s41598-024-62723-7 [details]
- Meijer, W. C., & Gorter, J. A. (2024). Role of blood-brain barrier dysfunction in the development of poststroke epilepsy. Epilepsia, 65(9), 2519-2536. https://doi.org/10.1111/epi.18072 [details]
- Ravizza, T., Scheper, M., Di Sapia, R., Gorter, J., Aronica, E., & Vezzani, A. (2024). mTOR and neuroinflammation in epilepsy: implications for disease progression and treatment. Nature Reviews Neuroscience, 25(5), 334-350. https://doi.org/10.1038/s41583-024-00805-1 [details]
- van Vliet, E. A., Scheper, M., Mills, J. D., Puhakka, N., Szydlowska, K., Ferracin, M., Lovisari, F., Soukupova, M., Zucchini, S., Srivastava, P. K., Johnson, M. R., Lukasiuk, K., Gorter, J. A., Aronica, E., Pitkänen, A., & Simonato, M. (2024). Circulating microRNAs and isomiRs as biomarkers for the initial insult and epileptogenesis in four experimental epilepsy models: The EPITARGET study. Epilepsia, 65(11), 3406-3420. https://doi.org/10.1111/epi.18134 [details]
2022
- Broekaart, D. W. M., Zimmer, T. S., Cohen, S. T., Tessers, R., Anink, J. J., de Vries, H. E., Gorter, J. A., Prades, R., Aronica, E., & van Vliet, E. A. (2022). The Gelatinase Inhibitor ACT-03 Reduces Gliosis in the Rapid Kindling Rat Model of Epilepsy, and Attenuates Inflammation and Loss of Barrier Integrity In Vitro. Biomedicines, 10(9), Article 2117. https://doi.org/10.3390/biomedicines10092117 [details]
- Drion, C. M., Kooijman, L., Chan, D., Berkhout, J., van Vliet, E. A., Wadman, W. J., & Gorter, J. A. (2022). No persistent effects of intracerebral curcumin administration on seizure progression and neuropathology in the kindling rat model for temporal lobe epilepsy. Epilepsy Research, 181, Article 106873. https://doi.org/10.1016/j.eplepsyres.2022.106873 [details]
2021
- Broekaart, D. W. M., Bertran, A., Jia, S., Korotkov, A., Senkov, O., Bongaarts, A., Mills, J. D., Anink, J. J., Seco, J., Baaijen, J. C., Idema, S., Chabrol, E., Becker, A., Wadman, W. J., Tarragó, T., Gorter, J. A., Aronica, E., Prades, R., Dityatev, A., & van Vliet, E. A. (2021). The matrix metalloproteinase inhibitor IPR-179 has antiseizure and antiepileptogenic effects. The journal of clinical investigation, 131(1), Article e138332. https://doi.org/10.1172/JCI138332 [details]
- Broekaart, D. W. M., Korotkov, A., Gorter, J. A., & van Vliet, E. A. (2021). Perivascular inflammation and extracellular matrix alterations in blood-brain barrier dysfunction and epilepsy. In D. Jangiro, A. Nehlig, & N. Marchi (Eds.), Inflammation and epilepsy: new vistas (pp. 71-106). (Progress in Infammation Research; Vol. 88). Springer. https://doi.org/10.1007/978-3-030-67403-8_4 [details]
- Zimmer, T. S., David, B., Broekaart, D. W. M., Schidlowski, M., Ruffolo, G., Korotkov, A., van der Wel, N. N., van Rijen, P. C., Mühlebner, A., van Hecke, W., Baayen, J. C., Idema, S., François, L., van Eyll, J., Dedeurwaerdere, S., Kessels, H. W., Surges, R., Rüber, T., Gorter, J. A., ... Aronica, E. (2021). Seizure-mediated iron accumulation and dysregulated iron metabolism after status epilepticus and in temporal lobe epilepsy. Acta Neuropathologica, 142(4), 729-759. https://doi.org/10.1007/s00401-021-02348-6 [details]
2020
- Korotkov, A., Broekaart, D. W. M., Banchaewa, L., Pustjens, B., van Scheppingen, J., Anink, J. J., Baayen, J. C., Idema, S., Gorter, J. A., van Vliet, E. A., & Aronica, E. (2020). microRNA-132 is overexpressed in glia in temporal lobe epilepsy and reduces the expression of pro-epileptogenic factors in human cultured astrocytes. GLIA, 68(1), 60-75. https://doi.org/10.1002/glia.23700 [details]
- van Vliet, E. A., Ndode-Ekane, X. E., Lehto, L. J., Gorter, J. A., Andrade, P., Aronica, E., Gröhn, O., & Pitkänen, A. (2020). Long-lasting blood-brain barrier dysfunction and neuroinflammation after traumatic brain injury. Neurobiology of Disease, 145, Article 105080. https://doi.org/10.1016/j.nbd.2020.105080 [details]
2019
- Drion, C. M., Kooijman, L., Aronica, E., van Vliet, E. A., Wadman, W. J., Chameau, P., & Gorter, J. A. (2019). Curcumin reduces development of seizurelike events in the hippocampal-entorhinal cortex slice culture model for epileptogenesis. Epilepsia, 60(4), 605-614. https://doi.org/10.1111/epi.14667 [details]
- Gorter, J. A., Aronica, E., & van Vliet, E. A. (2019). The Roof is Leaking and a Storm is Raging: Repairing the Blood-Brain Barrier in the Fight Against Epilepsy. Epilepsy currents, 19(3), 177-181. https://doi.org/10.1177/1535759719844750 [details]
2018
- Broekaart, D. W. M., Anink, J. J., Baayen, J. C., Idema, S., de Vries, H. E., Aronica, E., Gorter, J. A., & van Vliet, E. A. (2018). Activation of the innate immune system is evident throughout epileptogenesis and is associated with blood-brain barrier dysfunction and seizure progression. Epilepsia, 59(10), 1931-1944. https://doi.org/10.1111/epi.14550 [details]
- Drion, C. M., van Scheppingen, J., Arena, A., Geijtenbeek, K. W., Kooijman, L., van Vliet, E. A., Aronica, E., & Gorter, J. A. (2018). Effects of rapamycin and curcumin on inflammation and oxidative stress in vitro and in vivo - in search of potential anti-epileptogenic strategies for temporal lobe epilepsy. Journal of neuroinflammation, 15, Article 212. https://doi.org/10.1186/s12974-018-1247-9 [details]
- Gorter, J. A., van Vliet, E. A., Dedeurwaerdere, S., Buchanan, G. F., Friedman, D., Borges, K., Grabenstatter, H., Lukasiuk, K., Scharfman, H. E., & Nehlig, A. (2018). A companion to the preclinical common data elements for physiologic data in rodent epilepsy models. A report of the TASK3 Physiology Working Group of the ILAE/AES Joint Translational Task Force. Epilepsia Open, 3(S1), 69-89. https://doi.org/10.1002/epi4.12261 [details]
- Korotkov, A., Broekaart, D. W. M., van Scheppingen, J., Anink, J. J., Baayen, J. C., Idema, S., Gorter, J. A., Aronica, E., & van Vliet, E. A. (2018). Increased expression of matrix metalloproteinase 3 can be attenuated by inhibition of microRNA-155 in cultured human astrocytes. Journal of neuroinflammation, 15, Article 211. https://doi.org/10.1186/s12974-018-1245-y [details]
2017
- Aronica, E., Bauer, S., Bozzi, Y., Caleo, M., Dingledine, R., Gorter, J. A., Henshall, D. C., Kaufer, D., Koh, S., Löscher, W., Louboutin, J-P., Mishto, M., Norwood, B. A., Palma, E., Poulter, M. O., Terrone, G., Vezzani, A., & Kaminski, R. M. (2017). Neuroinflammatory targets and treatments for epilepsy validated in experimental models. Epilepsia, 58(S3), 27-38. https://doi.org/10.1111/epi.13783 [details]
- Aronica, E., Mühlebner, A., van Vliet, E. A., & Gorter, J. A. (2017). Characterization of pathology. In A. Pitkänen, P. S. Buckmaster, A. S. Galanopoulou, & S. L. Moshé (Eds.), Models of seizures and epilepsy (2nd ed., pp. 139-160). Academic Press. https://doi.org/10.1016/B978-0-12-804066-9.00011-0 [details]
- Broekaart, D. W. M., van Scheppingen, J., Geijtenbeek, K. W., Zuidberg, M. R. J., Anink, J. J., Baayen, J. C., Muhlebner, A., Aronica, E., Gorter, J. A., & van Vliet, E. A. (2017). Increased expression of (immuno)proteasome subunits during epileptogenesis is attenuated by inhibition of the mammalian target of rapamycin pathway. Epilepsia, 58(8), 1462-1472. Advance online publication. https://doi.org/10.1111/epi.13823 [details]
- Dingledine, R., Coulter, D. A., Fritsch, B., Gorter, J. A., Lelutiu, N., McNamara, J., Nadler, J. V., Pitkänen, A., Rogawski, M. A., Skene, P., Sloviter, R. S., Wang, Y., Wadman, W. J., Wasterlain, C., & Roopra, A. (2017). Transcriptional profile of hippocampal dentate granule cells in four rat epilepsy models. Scientific Data, 4, Article 170061. https://doi.org/10.1038/sdata.2017.61 [details]
- Gorter, J. A., & van Vliet, E. A. (2017). Post-status epilepticus models: electrical stimulation. In A. Pitkänen, P. S. Buckmaster, A. S. Galanopoulou, & S. L. Moshé (Eds.), Models of seizures and epilepsy (2nd ed., pp. 637-650). Academic Press. https://doi.org/10.1016/B978-0-12-804066-9.00044-4 [details]
- Korotkov, A., Mills, J. D., Gorter, J. A., van Vliet, E. A., & Aronica, E. (2017). Systematic review and meta-analysis of differentially expressed miRNAs in experimental and human temporal lobe epilepsy. Scientific Reports, 7, Article 11592. https://doi.org/10.1038/s41598-017-11510-8 [details]
- Lapinlampi, N., Melin, E., Aronica, E., Bankstahl, J. P., Becker, A., Bernard, C., Gorter, J. A., Gröhn, O., Lipsanen, A., Lukasiuk, K., Löscher, W., Paananen, J., Ravizza, T., Roncon, P., Simonato, M., Vezzani, A., Kokaia, M., & Pitkänen, A. (2017). Common data elements and data management: Remedy to cure underpowered preclinical studies. Epilepsy Research, 129, 87-90. Advance online publication. https://doi.org/10.1016/j.eplepsyres.2016.11.010 [details]
- Mills, J. D., Iyer, A. M., van Scheppingen, J., Bongaarts, A., Anink, J. J., Janssen, B., Zimmer, T. S., Spliet, W. G., van Rijen, P. C., Jansen, F. E., Feucht, M., Hainfellner, J. A., Krsek, P., Zamecnik, J., Kotulska, K., Jozwiak, S., Jansen, A., Lagae, L., Curatolo, P., ... Aronica, E. (2017). Coding and small non-coding transcriptional landscape of tuberous sclerosis complex cortical tubers: implications for pathophysiology and treatment. Scientific Reports, 7, Article 8089. https://doi.org/10.1038/s41598-017-06145-8 [details]
- Srivastava, P. K., Roncon, P., Lukasiuk, K., Gorter, J. A., Aronica, E., Pitkänen, A., Petretto, E., Johnson, M. R., & Simonato, M. (2017). Meta-Analysis of MicroRNAs Dysregulated in the Hippocampal Dentate Gyrus of Animal Models of Epilepsy. eNeuro, 4(6), Article e0152. https://doi.org/10.1523/ENEURO.0152-17.2017 [details]
- van Vliet, E. A., & Gorter, J. A. (2017). Electrical stimulation seizure models. In A. Pitkänen, P. S. Buckmaster, A. S. Galanopoulou, & S. L. Moshé (Eds.), Models of seizures and epilepsy (2nd ed., pp. 474-488). Academic Press. https://doi.org/10.1016/B978-0-12-804066-9.00034-1 [details]
- van Vliet, E. A., Puhakka, N., Mills, J. D., Srivastava, P. K., Johnson, M. R., Roncon, P., Das Gupta, S., Karttunen, J., Simonato, M., Lukasiuk, K., Gorter, J. A., Aronica, E., & Pitkänen, A. (2017). Standardization procedure for plasma biomarker analysis in rat models of epileptogenesis: Focus on circulating microRNAs. Epilepsia, 58(12), 2013–2024. https://doi.org/10.1111/epi.13915 [details]
2016
- Drion, C. M., Borm, L. E., Kooijman, L., Aronica, E., Wadman, W. J., Hartog, A. F., van Vliet, E. A., & Gorter, J. A. (2016). Effects of rapamycin and curcumin treatment on the development of epilepsy after electrically induced status epilepticus in rats. Epilepsia, 57(5), 688-697. Advance online publication. https://doi.org/10.1111/epi.13345 [details]
- Gorter, J. A., van Vliet, E. A., & Lopes da Silva, F. H. (2016). Which insights have we gained from the kindling and post-status epilepticus models? Journal of Neuroscience Methods, 260, 96-108. Advance online publication. https://doi.org/10.1016/j.jneumeth.2015.03.025 [details]
- Pitkänen, A., Löscher, W., Vezzani, A., Becker, A. J., Simonato, M., Lukasiuk, K., Gröhn, O., Bankstahl, J. P., Friedman, A., Aronica, E., Gorter, J. A., Ravizza, T., Sisodiya, S. M., Kokaia, M., & Beck, H. (2016). Advances in the development of biomarkers for epilepsy. Lancet Neurology, 15(8), 843-856. https://doi.org/10.1016/S1474-4422(16)00112-5 [details]
- van Vliet, E. A., Otte, W. M., Wadman, W. J., Aronica, E., Kooij, G., de Vries, H. E., Dijkhuizen, R. M., & Gorter, J. A. (2016). Blood-brain barrier leakage after status epilepticus in rapamycin-treated rats I: Magnetic resonance imaging. Epilepsia, 57(1), 59-69. Advance online publication. https://doi.org/10.1111/epi.13246 [details]
- van Vliet, E. A., Otte, W. M., Wadman, W. J., Aronica, E., Kooij, G., de Vries, H. E., Dijkhuizen, R. M., & Gorter, J. A. (2016). Blood-brain barrier leakage after status epilepticus in rapamycin-treated rats II: Potential mechanisms. Epilepsia, 57(1), 70-78. Advance online publication. https://doi.org/10.1111/epi.13245 [details]
2015
- Gorter, J. A., van Vliet, E. A., & Aronica, E. (2015). Status epilepticus, blood-brain barrier disruption, inflammation, and epileptogenesis. Epilepsy & Behavior, 49, 13-16. Advance online publication. https://doi.org/10.1016/j.yebeh.2015.04.047 [details]
- Shen, H-Y., van Vliet, E. A., Bright, K-A., Hanthorn, M., Lytle, N. K., Gorter, J., Aronica, E., & Boison, D. (2015). Glycine transporter 1 is a target for the treatment of epilepsy. Neuropharmacology, 99, 554-565. Advance online publication. https://doi.org/10.1016/j.neuropharm.2015.08.031 [details]
- van Vliet, E. A., Aronica, E., & Gorter, J. A. (2015). Blood-brain barrier dysfunction, seizures and epilepsy. Seminars in Cell & Developmental Biology, 38, 26-34. Advance online publication. https://doi.org/10.1016/j.semcdb.2014.10.003 [details]
- van der Vinne, V., Gorter, J. A., Riede, S. J., & Hut, R. A. (2015). Diurnality as an energy-saving strategy: energetic consequences of temporal niche switching in small mammals. Journal of Experimental Biology, 218(16), 2585-2593. https://doi.org/10.1242/jeb.119354 [details]
2014
- Bielefeld, P., van Vliet, E. A., Gorter, J. A., Lucassen, P. J., & Fitzsimons, C. P. (2014). Different subsets of newborn granule cells: a possible role in epileptogenesis? European Journal of Neuroscience, 39(1), 1-11. https://doi.org/10.1111/ejn.12387 [details]
- Gorter, J. A., Iyer, A., White, I., Colzi, A., van Vliet, E. A., Sisodiya, S., & Aronica, E. (2014). Hippocampal subregion-specific microRNA expression during epileptogenesis in experimental temporal lobe epilepsy. Neurobiology of Disease, 62, 508-520. Advance online publication. https://doi.org/10.1016/j.nbd.2013.10.026 [details]
- Holtman, L., van Vliet, E., Appeldoorn, C., Gaillard, P. J., de Boer, M., Dorland, R., Wadman, W., & Gorter, J. (2014). Glutathione pegylated liposomal methylprednisolone administration after the early phase of status epilepticus did not modify epileptogenesis in the rat. Epilepsy Research, 108(3), 396-404. https://doi.org/10.1016/j.eplepsyres.2014.01.010 [details]
- Zellinger, C., Salvamoser, J. D., Soerensen, J., van Vliet, E. A., Aronica, E., Gorter, J., & Potschka, H. (2014). Pre-treatment with the NMDA receptor glycine-binding site antagonist L-701, 324 improves pharmacosensitivity in a mouse kindling model. Epilepsy Research, 108(4), 634-643. https://doi.org/10.1016/j.eplepsyres.2014.02.012 [details]
- van Vliet, E. A., Aronica, E., & Gorter, J. A. (2014). Role of blood-brain barrier in temporal lobe epilepsy and pharmacoresistance. Neuroscience, 277, 455-473. https://doi.org/10.1016/j.neuroscience.2014.07.030 [details]
- van Vliet, E. A., Otte, W. M., Gorter, J. A., Dijkhuizen, R. M., & Wadman, W. J. (2014). Longitudinal assessment of blood-brain barrier leakage during epileptogenesis in rats. A quantitative MRI study. Neurobiology of Disease, 63, 74-84. https://doi.org/10.1016/j.nbd.2013.11.019 [details]
2013
- Holtman, L., van Vliet, E. A., Aronica, E., Wouters, D., Wadman, W. J., & Gorter, J. A. (2013). Blood plasma inflammation markers during epileptogenesis in post-status epilepticus rat model for temporal lobe epilepsy. Epilepsia, 54(4), 589-595. Advance online publication. https://doi.org/10.1111/epi.12112 [details]
- Qiao, X., Werkman, T. R., Gorter, J. A., Wadman, W. J., & van Vliet, E. A. (2013). Expression of sodium channel α subunits 1.1, 1.2 and 1.6 in rat hippocampus after kainic acid-induced epilepsy. Epilepsy Research, 106(1-2), 17-28. https://doi.org/10.1016/j.eplepsyres.2013.06.006 [details]
2012
- Aronica, E., Sisodiya, S. M., & Gorter, J. A. (2012). Cerebral expression of drug transporters in epilepsy. Advanced drug delivery reviews, 64(10), 919-929. Advance online publication. https://doi.org/10.1016/j.addr.2011.11.008 [details]
- Galanopoulou, A. S., Gorter, J. A., & Cepeda, C. (2012). Finding a better drug for epilepsy: the mTOR pathway as an antiepileptogenic target. Epilepsia, 53(7), 1119-1130. https://doi.org/10.1111/j.1528-1167.2012.03506.x [details]
- Gorter, J. A., & Potschka, H. (2012). Drug resistance. In J. L. Noebels, M. Avoli, M. A. Rogawski, R. W. Olsen, & A. V. Delgado-Escueta (Eds.), Jasper's basic mechanisms of the epilepsies (NCBI Bookshelf Online Book Version; No. NBK50785). National Centre for Biotechnology Information. http://www.ncbi.nlm.nih.gov/books/NBK98215/ [details]
- Iyer, A., Zurolo, E., Prabowo, A., Fluiter, K., Spliet, W. G. M., van Rijen, P. C., Gorter, J. A., & Aronica, E. (2012). MicroRNA-146a: a key regulator of astrocyte-mediated inflammatory response. PLoS ONE, 7(9), Article e44789. https://doi.org/10.1371/journal.pone.0044789 [details]
- Lopes da Silva, F. H., Gorter, J. A., & Wadman, W. J. (2012). Epilepsy as a dynamic disease of neuronal networks. In H. Stefan, & W. H. Theodore (Eds.), Epilepsy. - Pt. 1: Basic principles and diagnosis (pp. 35-62). (Handbook of clinical neurology; No. 107). Elsevier. https://doi.org/10.1016/B978-0-444-52898-8.00003-3 [details]
- Zurolo, E., de Groot, M., Iyer, A., Anink, J., van Vliet, E. A., Heimans, J. J., Reijneveld, J. C., Gorter, J. A., & Aronica, E. (2012). Regulation of Kir4.1 expression in astrocytes and astrocytic tumors: a role for interleukin-1 β. Journal of neuroinflammation, 9, Article 280. https://doi.org/10.1186/1742-2094-9-280 [details]
- van Vliet, E. A., Forte, G., Holtman, L., den Burger, J. C. G., Sinjewel, A., de Vries, H. E., Aronica, E., & Gorter, J. A. (2012). Inhibition of mammalian target of rapamycin reduces epileptogenesis and blood-brain barrier leakage but not microglia activation. Epilepsia, 53(7), 1254-1263. https://doi.org/10.1111/j.1528-1167.2012.03513.x [details]
2011
- Aronica, E., Iyer, A., Zurolo, E., & Gorter, J. A. (2011). Ontogenetic modifications of neuronal excitability during brain maturation: developmental changes of neurotransmitter receptors. Epilepsia, 52(S8), 3-5. https://doi.org/10.1111/j.1528-1167.2011.03222.x [details]
- Aronica, E., Zurolo, E., Iyer, A., de Groot, M., Anink, J., Carbonell, C., van Vliet, E. A., Baayen, J. C., Boison, D., & Gorter, J. A. (2011). Upregulation of adenosine kinase in astrocytes in experimental and human temporal lobe epilepsy. Epilepsia, 52(9), 1645-1655. https://doi.org/10.1111/j.1528-1167.2011.03115.x [details]
- Holtman, L., van Vliet, E. A., Baas, F., Aronica, E., & Gorter, J. A. (2011). Complement protein 6 deficiency in PVG/c rats does not lead to neuroprotection against seizure induced cell death. Neuroscience, 188, 109-116. https://doi.org/10.1016/j.neuroscience.2011.05.003 [details]
- van Vliet, E. A., Holtman, L., Aronica, E., Schmitz, L. J. M., Wadman, W. J., & Gorter, J. A. (2011). Atorvastatin treatment during epileptogenesis in a rat model for temporal lobe epilepsy. Epilepsia, 52(7), 1319-1330. https://doi.org/10.1111/j.1528-1167.2011.03073.x [details]
2010
- Aronica, E., Fluiter, K., Iyer, A., Zurolo, E., Vreijling, J., van Vliet, E. A., Baayen, J. C., & Gorter, J. A. (2010). Expression pattern of miR-146a, an inflammation-associated microRNA, in experimental and human temporal lobe epilepsy. European Journal of Neuroscience, 31(6), 1100-1107. https://doi.org/10.1111/j.1460-9568.2010.07122.x [details]
- Boer, K., Crino, P. B., Gorter, J. A., Nellist, M., Jansen, F. E., Spliet, W. G. M., van Rijen, P. C., Wittink, F. R. A., Breit, T. M., Troost, D., Wadman, W. J., & Aronica, E. M. A. (2010). Gene expression analysis of tuberous sclerosis complex cortical tubers reveals increased expression of adhesion and inflammatory factors. Brain Pathology, 20(4), 704-719. https://doi.org/10.1111/j.1750-3639.2009.00341.x [details]
- Gorter, J. (2010). Microarray-studies bij epileptische ratten indiceren nieuwe therapeutische strategieën. Epilepsie, 8(4), 12-15. http://www.epilepsieliga.nl/Tijdschrift-Epilepsie/5/16/84/0/december-2010/ [details]
- Gorter, J. A., Zurolo, E., Iyer, A., Fluiter, K., van Vliet, E. A., Baayen, J. C., & Aronica, E. (2010). Induction of sodium channel Nax (SCN7A) expression in rat and human hippocampus in temporal lobe epilepsy. Epilepsia, 51(9), 1791-1800. https://doi.org/10.1111/j.1528-1167.2010.02678.x [details]
- Holtman, L., van Vliet, E. A., Edelbroek, P. M., Aronica, E., & Gorter, J. A. (2010). Cox-2 inhibition can lead to adverse effects in a rat model for temporal lobe epilepsy. Epilepsy Research, 91(1), 49-56. https://doi.org/10.1016/j.eplepsyres.2010.06.011 [details]
- Iyer, A. M., Zurolo, E., Boer, K., Baayen, J. C., Giangaspero, F., Arcella, A., Di Gennaro, G. C., Esposito, V., Spliet, W. G. M., van Rijen, P. C., Troost, D., Gorter, J. A., & Aronica, E. (2010). Tissue plasminogen activator and urokinase plasminogen activator in human epileptogenic pathologies. Neuroscience, 167(3), 929-945. https://doi.org/10.1016/j.neuroscience.2010.02.047 [details]
- Iyer, A., Zurolo, E., Spliet, W. G. M., van Rijen, P. C., Baayen, J. C., Gorter, J. A., & Aronica, E. (2010). Evaluation of the innate and adaptive immunity in type I and type II focal cortical dysplasias. Epilepsia, 51(9), 1763-1773. https://doi.org/10.1111/j.1528-1167.2010.02547.x [details]
- Zurolo, E., Iyer, A. M., Spliet, W. G. M., van Rijen, P. C., Troost, D., Gorter, J. A., & Aronica, E. (2010). CB1 and CB2 cannabinoid receptor expression during development and in epileptogenic developmental pathologies. Neuroscience, 170(1), 28-41. https://doi.org/10.1016/j.neuroscience.2010.07.004 [details]
- van Vliet, E. A., Edelbroek, P. M., & Gorter, J. A. (2010). Improved seizure control by alternating therapy of levetiracetam and valproate in epileptic rats. Epilepsia, 51(3), 362-370. https://doi.org/10.1111/j.1528-1167.2009.02261.x [details]
- van Vliet, E. A., Zibell, G., Pekcec, A., Schlichtiger, J., Edelbroek, P. M., Holtman, L., Aronica, E., Gorter, J. A., & Potschka, H. (2010). COX-2 inhibition controls P-glycoprotein expression and promotes brain delivery of phenytoin in chronic epileptic rats. Neuropharmacology, 58(2), 404-412. https://doi.org/10.1016/j.neuropharm.2009.09.012 [details]
2009
- Aronica, E., Boer, K., Doorn, K. J., Zurolo, E., Spliet, W. G. M., van Rijen, P. C., Baayen, J. C., Gorter, J. A., & Jeromin, A. (2009). Expression and localization of voltage dependent potassium channel Kv4.2 in epilepsy associated focal lesions. Neurobiology of Disease, 36(1), 81-95. https://doi.org/10.1016/j.nbd.2009.06.016 [details]
- Gorter, J. A., Lopes da Silva, F. H., & Aronica, E. (2009). Patterns of gene expression in epileptogenesis: Micro-Array studies in rats. In P. A. Schwartzkroin (Ed.), Encyclopedia of basic epilepsy research (Vol. 1, pp. 240-250). Elsevier. https://doi.org/10.1016/B978-012373961-2.00017-5 [details]
- Holtman, L., van Vliet, E. A., van Schaik, R., Queiroz, C. M., Aronica, E., & Gorter, J. A. (2009). Effects of SC58236, a selective COX-2 inhibitor, on epileptogenesis and spontaneous seizures in a rat model for temporal lobe epilepsy. Epilepsy Research, 84(1), 56-66. https://doi.org/10.1016/j.eplepsyres.2008.12.006 [details]
- Lopes da Silva, F. H., & Gorter, J. A. (2009). Epileptogenesis and Plasticity. In P. A. Schwartzkroin (Ed.), Encyclopedia of basic epilepsy research. - Vol. 1 (pp. 221-227). Elsevier. https://doi.org/10.1016/B978-012373961-2.00265-4 [details]
- Pekcec, A., Unkrüer, B., Schlichtiger, J., Soerensen, J., Hartz, A. M. S., Bauer, B., van Vliet, E. A., Gorter, J. A., & Potschka, H. (2009). Targeting prostaglandin E2 EP1 receptors prevents seizure-associated P-glycoprotein up-regulation. The Journal of Pharmacology and experimental Therapeutics, 330(3), 939-947. https://doi.org/10.1124/jpet.109.152520 [details]
- Queiroz, C. M., Gorter, J. A., Lopes da Silva, F. H., & Wadman, W. J. (2009). Dynamics of evoked local field potentials in the hippocampus of epileptic rats with spontaneous seizures. Journal of Neurophysiology, 101(3), 1588-1597. https://doi.org/10.1152/jn.90770.2008 [details]
- Toering, S. T., Boer, K., de Groot, M., Troost, D., Heimans, J. J., Spliet, W. G. M., van Rijen, P. C., Jansen, F. E., Gorter, J. A., Reijneveld, J. C., & Aronica, E. (2009). Expression patterns of synaptic vesicle protein 2A in focal cortical dysplasia and TSC-cortical tubers. Epilepsia, 50(6), 1409-1418. https://doi.org/10.1111/j.1528-1167.2008.01955.x [details]
- van Vliet, E. A., Aronica, E. M. A., Redeker, S., Boer, K., & Gorter, J. A. (2009). Decreased expression of synaptic vesicle protein 2A, the binding site for levetiracetam, during epileptogenesis and chronic epilepsy. Epilepsia, 50(3), 422-433. https://doi.org/10.1111/j.1528-1167.2008.01727.x [details]
2008
- Aronica, E., Boer, K., Becker, A., Redeker, S., van Rijen, P. C., Wittink, F., Breit, T., Spliet, W. G. M., Wadman, W. J., Lopes da Silva, F. H., Troost, D., & Gorter, J. A. (2008). Gene expression profile analysis of epilepsy-associated gangliogliomas. Neuroscience, 151(1), 272-292. https://doi.org/10.1016/j.neuroscience.2007.10.036 [details]
- Boer, K., Troost, D., Spliet, W. G. M., van Rijen, P. C., Gorter, J. A., & Aronica, E. M. A. (2008). Cellular distribution of vascular endothelial growth factor A (VEGFA) and B (VEGFB) and VEGF receptors 1 and 2 in focal cortical dysplasia type IIB. Acta Neuropathologica, 115(6), 683-696. https://doi.org/10.1007/s00401-008-0354-6 [details]
- Boer, K., Troost, D., Timmermans, W., Gorter, J. A., Spliet, W. G. M., Nellist, M., Jansen, F., & Aronica, E. (2008). Cellular localization of metabotropic glutamate receptors in cortical tubers and subependymal giant cell tumors of tuberous sclerosis complex. Neuroscience, 156(1), 203-215. https://doi.org/10.1016/j.neuroscience.2008.06.073 [details]
- van Vliet, E. A., van Schaik, R., Edelbroek, P. M., Lopes da Silva, F. H., Wadman, W. J., & Gorter, J. A. (2008). Development of tolerance to levetiracetam in rats with chronic epilepsy. Epilepsia, 49(7), 1151-1159. https://doi.org/10.1111/j.1528-1167.2007.01516.x [details]
2016
- Gorter, J. A., Werkman, T. R., & Chameau, P. J. P. (2016). Mogelijk aanknopingspunt voor nieuwe medicijnen Cannabis en epilepsie, een interessant duo. Epilepsie Magazine.
2009
- Gorter, J. (2009). Leukocyten veroorzaken lekkage van de bloedhersenbarrière met epilepsie tot gevolg. Epilepsie, 7(2), 17-18. http://www.epilepsieliga.nl/Tijdschrift-Epilepsie/5/16/18/0/juni-2009/ [details]
Membership / relevant position
- Gorter, J. A. (2016-). Member of the Scientific Advisory Board, Dutch Epilepsy Fund.
Journal editor
- Gorter, J. A. (reviewer) (2016-). Epilepsia Open (Journal).
Talk / presentation
- Gorter, J. A. (speaker) (14-10-2016). Progress in the field since 2010, IIE2016 Milan, 13-15 October 2016; .
- Gorter, J. A. (invited speaker) (14-10-2016). Rapamycin effects on BBB leakage, inflammation, epileptogenesis and seizures, IIE2016 Milan, 13-15 October 2016; .
This list of publications is extracted from the UvA-Current Research Information System. Questions? Ask the library or the Pure staff of your faculty / institute. Log in to Pure to edit your publications. Log in to Personal Page Publication Selection tool to manage the visibility of your publications on this list. -
Ancillary activities
- No ancillary activities
Rozeboom, A., Broekaart, D. W. M., Anink, J. J., Boonkamp, L., Idema, S., Teunissen, C. E., Aronica, E., Gorter, J. A., & van Vliet, E. A. (2025). Cellular expression of low-density lipoprotein receptor-related protein 1 and amyloid beta deposition in human and rat epileptogenic brain. Experimental Neurology, 386, Article 115149.