Central to the research of our group is the molecular stress physiology of microorganisms at the boundary of death, survival and growth. At the heart of our research lies an integrative analysis of cellular response at the level of gene-expression, protein activity and metabolism towards both intrinsic and externally imposed stress. Quantitative analysis approaches are used to identify the most important levels of regulation of homeostasis including all state of the art molecular biology, proteomics, various advanced microscopical techniques as well as controlled cell culturing systems. Externally imposed stresses include compounds and treatments widely used to prevent and treat infection. We are a member of the Netherlands Institute for Systems Biology and have major contacts with the food and pharma industry focussing on the use of our data for new target identification.

Positioning MBMFS within Swammerdam Institute for Life Sciences

• Research lines Molecular Biology and Microbial Food Safety