prof. dr. A.P. (Arie) Otte

  • Faculty of Science
    Swammerdam Institute for Life Sciences
  • Visiting address
    Science Park A
    Science Park 904  
  • Postal address:
    Postbus  94215
    1090 GE  Amsterdam


  • Hoeksema, F., Hamer, K., Siep, M., Verhees, J. A., & Otte, A. P. (2011). Placing the RPL32 Promoter Upstream of a Second Promoter Results in a Strongly Increased Number of Stably Transfected Mammalian Cell Lines That Display High Protein Expression Levels. Biotechnology Research International, 2011, 492875. DOI: 10.4061/2011/492875  [details] 
  • Hoeksema, F., van Blokland, R., Siep, M., Hamer, K., Siersma, T., den Blaauwen, J., ... Otte, A. P. (2011). The use of a stringent selection system allows the identification of DNA elements that augment gene expression. Molecular Biotechnology, 48(1), 19-29. DOI: 10.1007/s12033-010-9344-8  [details] 
  • van Blokland, H. J. M., Hoeksema, F., Siep, M., Otte, A. P., & Verhees, J. A. (2011). Methods to create a stringent selection system for mammalian cell lines. Cytotechnology, 63(4), 371-384. DOI: 10.1007/s10616-011-9354-9  [details] 
  • Li, X., Isono, K., Yamada, D., Endo, T. A., Endoh, M., Shinga, J., ... Koseki, H. (2011). Mammalian polycomb-like Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate polycomb activity both at the Hox gene cluster and at Cdkn2a genes. Molecular and Cellular Biology, 31(2), 351-364. DOI: 10.1128/MCB.00259-10  [details] 


  • Inoue, K., Kohda, T., Sugimoto, M., Sado, T., Ogonuki, N., Matoba, S., ... Ogura, A. (2010). Impeding Xist expression from the active X chromosome improves mouse somatic cell nuclear transfer. Science, 330(6003), 496-499. DOI: 10.1126/science.1194174  [details] 


  • Boukarabila, H., Saurin, A. J., Batsché, E., Mossadegh, N., van Lohuizen, M., Otte, A. P., ... Duprez, E. (2009). The PRC1 Polycomb group complex interacts with PLZF/RARA to mediate leukemic transformation. Genes & Development, 23(10), 1195-1206. DOI: 10.1101/gad.512009  [details] 
  • Fluge, Ø., Gravdal, K., Carlsen, E., Vonen, B., Kjellevold, K., Refsum, S., ... Dahl, O. (2009). Expression of EZH2 and Ki-67 in colorectal cancer and associations with treatment response and prognosis. The British journal of cancer, 101(8), 1282-1289. DOI: 10.1038/sj.bjc.6605333  [details] 


  • Vékony, H., Raaphorst, F. M., Otte, A. P., van Lohuizen, M., Leemans, C. R., van der Waal, I., & Bloemena, E. (2008). High expression of Polycomb group protein EZH2 predicts poor survival in salivary gland adenoid cystic carcinoma. Journal of clinical pathology, 61(6), 744-749. DOI: 10.1136/jcp.2007.054262  [details] 
  • Endoh, M., Endo, T. A., Endoh, T., Fujimura, Y., Ohara, O., Toyoda, T., ... Koseki, H. (2008). Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity. Development - The Company of Biologists, 135(8), 1513-1524. DOI: 10.1242/dev.014340  [details] 
  • Engelsen, I. B., Mannelqvist, M., Stefansson, I. M., Carter, S. L., Beroukhim, R., Øyan, A. M., ... Salvesen, H. B. (2008). Low BMI-1 expression is associated with an activated BMI-1-driven signature, vascular invasion, and hormone receptor loss in endometrial carcinoma. The British journal of cancer, 98(10), 1662-1669. DOI: 10.1038/sj.bjc.6604360  [details] 
  • Puschendorf, M., Terranova, R., Boutsma, E., Mao, X., Isono, K., Brykczynska, U., ... Peters, A. H. F. M. (2008). PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos. Nature genetics, 40(4), 411-420. DOI: 10.1038/ng.99  [details] 
  • Terranova, R., Yokobayashi, S., Stadler, M. B., Otte, A. P., van Lohuizen, M., Orkin, S. H., & Peters, A. H. F. M. (2008). Polycomb group proteins Ezh2 and Rnf2 direct genomic contraction and imprinted repression in early mouse embryos. Developmental Cell, 15(5), 668-679. DOI: 10.1016/j.devcel.2008.08.015  [details] 
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  • No ancillary activities

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