prof. dr. J. (Jeroen) Hugenholtz

  • Faculty of Science
    Swammerdam Institute for Life Sciences
  • Visiting address
    Science Park A
    Science Park 904  Room number: 8,04
  • Postal address:
    Science Park  904
    1098 XH  Amsterdam
    T: 0205256424


  • Levering, J., Fiedler, T., Sieg, A., van Grinsven, K. W. A., Hering, S., Veith, N., ... Kummer, U. (2016). Genome-scale reconstruction of the Streptococcus pyogenes M49 metabolic network reveals growth requirements and indicates potential drug targets. Journal of Biotechnology, 232, 25-37. DOI: 10.1016/j.jbiotec.2016.01.035  [details] 
  • Tyler, C. A., Kopit, L., Doyle, C., Yu, A. O., Hugenholtz, J., & Marco, M. L. (2016). Polyol production during heterofermentative growth of the plant isolate Lactobacillus florum 2F. Journal of Applied Microbiology, 120(5), 1336-1345. DOI: 10.1111/jam.13108  [details] 





  • Levering, J., Musters, M. W., Bekker, M., Bellomo, D., Fiedler, T., de Vos, W. M., ... Teusink, B. (2012). Role of phosphate in the central metabolism of two lactic acid bacteria - a comparative systems biology approach. The FEBS Journal, 279(7), 1274-1290. DOI: 10.1111/j.1742-4658.2012.08523.x  [details] 


  • Fiedler, T., Bekker, M., Jonsson, M., Mehmeti, I., Pritzschke, A., Siemens, N., ... Kreikemeyer, B. (2011). Characterization of three lactic acid bacteria and their isogenic ldh deletion mutants shows optimization for Y(ATP) (cell mass produced per mole of ATP) at their physiological pHs. Applied and Environmental Microbiology, 77(2), 612-617. DOI: 10.1128/AEM.01838-10  [details] 
  • Santos, F., Spinler, J. K., Saulnier, D. M., Molenaar, D., Teusink, B., de Vos, W. M., ... Hugenholtz, J. (2011). Functional identification in Lactobacillus reuteri of a PocR-like transcription factor regulating glycerol utilization and vitamin B12 synthesis. Microbial Cell Factories, 10(55). [details] 


  • Goffin, P., van de Bunt, B., Giovane, M., Leveau, J. H. J., Höppener-Ogawa, S., Teusink, B., & Hugenholtz, J. (2010). Understanding the physiology of Lactobacillus plantarum at zero growth. Molecular Systems Biology, 6, 413. DOI: 10.1038/msb.2010.67  [details] 
  • LeBlanc, J. G., Sybesma, W., Starrenburg, M., Sesma, F., de Vos, W. M., Savoy de Giori, G., & Hugenholtz, J. (2010). Supplementation with engineered Lactococcus lactis improves the folate status in deficient rats. Nutrition, 26(7-8), 835-841. DOI: 10.1016/j.nut.2009.06.023  [details] 
  • LeBlanc, J. G., van Sinderen, D., Hugenholtz, J., Piard, J. C., Sesma, F., & Savoy de Giori, G. (2010). Risk assessment of genetically modified lactic acid bacteria using the concept of substantial equivalence. Current Microbiology, 61(6), 590-595. DOI: 10.1007/s00284-010-9657-7  [details] 
  • Maischberger, T., Mierau, I., Peterbauer, C. K., Hugenholtz, J., & Haltrich, D. (2010). High-level expression of Lactobacillus beta-galactosidases in Lactococcus lactis using the food-grade, nisin-controlled expression system NICE. Journal of Agricultural and Food Chemistry, 58(4), 2279-2287. DOI: 10.1021/jf902895g  [details] 


  • Bekaert, S., Storozhenko, S., Mehrshahi, P., Bennett, M. J., Lambert, W., Gregory III, J. F., ... Hanson, A. D. (2008). Folate biofortification in food plants. Trends in Plant Science, 13(1), 28-35. DOI: 10.1016/j.tplants.2007.11.001  [details] 
  • Santos, F., Vera, J. L., van der Heijden, R., Valdez, G., de Vos, W. M., Sesma, F., & Hugenholtz, J. (2008). The complete coenzyme B12 biosynthesis gene cluster of Lactobacillus reuteri CRL1098. Microbiology - SGM, 154(1), 81-93. DOI: 10.1099/mic.0.2007/011569-0  [details] 
  • Santos, F., Wegkamp, A., de Vos, W. M., Smid, E. J., & Hugenholtz, J. (2008). High-level folate production in fermented foods by the B12 producer Lactobacillus reuteri JCM1112. Applied and Environmental Microbiology, 74(10), 3291-3294. DOI: 10.1128/AEM.02719-07  [details] 
  • Sieuwerts, S., de Bok, F. A. M., Hugenholtz, J., & van Hylckama Vlieg, J. E. T. (2008). Unraveling microbial interactions in food fermentations: From classical to genomics approaches. Applied and Environmental Microbiology, 74(16), 4997-5007. DOI: 10.1128/AEM.00113-08  [details] 
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